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The inverse association of cancer and Alzheimer's: a bioenergetic mechanism

21 Feb 2013

Abstract excerpt

The sporadic forms of cancer and Alzheimer's disease (AD) are both age-related metabolic disorders. However, the molecular mechanisms underlying the two diseases are distinct: cancer is described by essentially limitless replicative potential, whereas neuronal death is a key feature of AD. Studies of the origin of both diseases indicate that their sporadic forms are the result of metabolic dysregulation, and a...

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PMID: 23427097
DOI: 10.1098/rsif.2013.0006

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