Maximal stress-induced transcription from the human HSP70 promoter requires interactions with the basal promoter elements independent of rotational alignment.

doi:10.1128/mcb.10.6.3125-3136.1990

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Article

Maximal stress-induced transcription from the human HSP70 promoter requires interactions with the basal promoter elements independent of rotational alignment.

Molecular and cellular biology - 1 Jun 1990

Williams G T, Morimoto R I

Abstract excerpt

Transcription of the human HSP70 gene is regulated by a complex array of cis-acting promoter elements that respond to conditions that include normal conditions of cell growth and induction following physiological stress. We have examined the requirements of the basal and inducible promoter elemen...

Topics

Base Sequence
Cell Division
Chromosome Deletion
Genes
Genetic Vectors
HeLa Cells
Heat-Shock Proteins
Hot Temperature
Humans
Kinetics
Metals
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Weight

Mutation

Plasmids

Promoter Regions, Genetic

RNA, Neoplasm

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 2342471
DOI: 10.1128/mcb.10.6.3125-3136.1990
PMCID: PMC360677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2342471-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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