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Article

Activation of the heat shock transcription factor by hypoxia in mammalian cells.

Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1990

Benjamin I J, Kröger B, Williams R S

Abstract excerpt

Members of the stress protein family such as HSP70 are induced in ischemic tissues and may contribute to the ability of cells to survive episodes of transient circulatory insufficiency. However, the biochemical events that lead to this induction, and their degree of similarity with pathways triggered by heat stress, have not been defined. In this study, we demonstrate that transient exposure of cultured C2C12...

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Identifiers

PMID: 1696723
DOI: 10.1073/pnas.87.16.6263
PMCID: PMC54513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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