Article
Genetic predisposition to higher body mass index or type 2 diabetes and leukocyte telomere length in the Nurses' Health Study.
PloS one - 1 Jan 2013
Du Mengmeng, Prescott Jennifer, Cornelis Marilyn C, Hankinson Susan E, Giovannucci Edward, Kraft Peter, De Vivo Immaculata
Abstract excerpt
BACKGROUND: Although cross-sectional studies have linked higher body mass index (BMI) and type 2 diabetes (T2D) to shortened telomeres, whether these metabolic conditions play a causal role in telomere biology is unknown. We therefore examined whether genetic predisposition to higher BMI or T2D was associated with shortened leukocyte telomere length (LTL). METHODOLOGY: We conducted an analysis of 3,968 women of...
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