Article
Genome-wide association study of relative telomere length.
PloS one - 10 May 2011
Prescott Jennifer, Kraft Peter, Chasman Daniel I, Savage Sharon A, Mirabello Lisa, Berndt Sonja I, Weissfeld Joel L, Han Jiali, Hayes Richard B, Chanock Stephen J, Hunter David J, De Vivo Immaculata
Abstract excerpt
Telomere function is essential to maintaining the physical integrity of linear chromosomes and healthy human aging. The probability of forming proper telomere structures depends on the length of the telomeric DNA tract. We attempted to identify common genetic variants associated with log relative telomere length using genome-wide genotyping data on 3,554 individuals from the Nurses' Health Study and the Prostate,...
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