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Article

Telomere length and metabolic syndrome traits: A Mendelian randomisation study

27 Jul 2021

Abstract excerpt

Abstract Observational studies have revealed associations between short leucocyte telomere length (LTL), a TL marker in somatic tissues and multiple Metabolic Syndrome (MetS) traits. Animal studies have supported these findings by showing that increased telomere attrition leads to adipose tissue dysfunction and insulin resistance. We investigated the associations between genetically instrumented LTL and MetS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34312982
DOI: 10.1111/acel.13445

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