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Article

Association mapping of the high-grade myopia MYP3 locus reveals novel candidates UHRF1BP1L, PTPRR, and PPFIA2.

Investigative ophthalmology & visual science - 21 Mar 2013

Hawthorne Felicia, Feng Sheng, Metlapally Ravikanth, Li Yi-Ju, Tran-Viet Khanh-Nhat, Guggenheim Jeremy A, Malecaze Francois, Calvas Patrick, Rosenberg Thomas, Mackey David A, Venturini Cristina, Hysi Pirro G, Hammond Christopher J, Young Terri L

Abstract excerpt

PURPOSE: Myopia, or nearsightedness, is a common ocular genetic disease for which over 20 candidate genomic loci have been identified. The high-grade myopia locus, MYP3, has been reported on chromosome 12q21-23 by four independent linkage studies. METHODS: We performed a genetic association study of the MYP3 locus in a family-based high-grade myopia cohort (n = 82) by genotyping 768 single-nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23422819
DOI: 10.1167/iovs.12-11102
PMCID: PMC3621505

Genes

PPFIA2
PTPRR
DEPDC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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