Article
An international collaborative family-based whole genome quantitative trait linkage scan for myopic refractive error.
Molecular vision - 1 Jan 2012
Abbott Diana, Li Yi-Ju, Guggenheim Jeremy A, Metlapally Ravikanth, Malecaze Francois, Calvas Patrick, Rosenberg Thomas, Paget Sandrine, Zayats Tetyana, Mackey David A, Feng Sheng, Young Terri L
Abstract excerpt
PURPOSE: To investigate quantitative trait loci linked to refractive error, we performed a genome-wide quantitative trait linkage analysis using single nucleotide polymorphism markers and family data from five international sites. METHODS: Genomic DNA samples from 254 families were genotyped by the Center for Inherited Disease Research using the Illumina Linkage Panel IVb. Quantitative trait linkage analysis was...
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