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Article

An international collaborative family-based whole-genome linkage scan for high-grade myopia.

Investigative ophthalmology & visual science - 1 Jul 2009

Li Yi-Ju, Guggenheim Jeremy A, Bulusu Anuradha, Metlapally Ravikanth, Abbott Diana, Malecaze Francois, Calvas Patrick, Rosenberg Thomas, Paget Sandrine, Creer Rosalind C, Kirov George, Owen Michael J, Zhao Bei, White Tristan, Mackey David A, Young Terri L

Abstract excerpt

PURPOSE: Several nonsyndromic high-grade myopia loci have been mapped primarily by microsatellite markers and a limited number of pedigrees. In this study, whole-genome linkage scans were performed for high-grade myopia, using single nucleotide polymorphisms (SNPs) in 254 families from five independent sites. METHODS: Genomic DNA samples from 1411 subjects were genotyped (Linkage Panel IVb; Illumina, San Diego,...

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Identifiers

PMID: 19324860
DOI: 10.1167/iovs.08-2781
PMCID: PMC3696634

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NPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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