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Article

Advances in the genetics of refractive errors: Contributions from the CREAM consortium.

Acta ophthalmologica - 1 May 2026

Li Sze Wai Rosa, He Xi, Terry Louise, Verhoeven Virginie J M, Lee Samantha Sze-Yee, Lingham Gareth, Guggenheim Jeremy A, Mackey David A, Saw Seang-Mei, Klaver Caroline C W, Pang Chi Pui

Abstract excerpt

The Consortium for Refractive Error and Myopia (CREAM) was established in 2011, bringing together an international team of researchers studying more than 30 cohorts. Since its establishment, CREAM has played a pivotal role in research investigating the genetics of myopia and other refractive errors, serving as a key driver of progress in the field. The aim of this review is to highlight the latest advances and...

Topics

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CRX gene
MAPT gene
PER3 gene
Genetic Predisposition to Disease
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Refraction, Ocular

Refractive Errors

Source

Open in PubMed Open full text

Identifiers

PMID: 41230783
DOI: 10.1111/aos.70025
PMCID: PMC13058672

Genes

ATM
CHST6
COL4A4
CRX
DDIT4
GRHL2
MAPT
P4HTM
PDCD6IP
PER3
SIX6
USH2A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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