Genetic interaction between pku300 and fbn2b controls endocardial cell proliferation and valve development in zebrafish.

Abstract excerpt

Abnormal cardiac valve morphogenesis is a common cause of human congenital heart disease. The molecular mechanisms regulating endocardial cell proliferation and differentiation into cardiac valves remain largely unknown, although great progress has been made on the endocardial contribution to the atrioventricular cushion and valve formation. We found that scotch tape(te382) (sco(te382)) encodes a novel...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Endocardium
• Share to Heart Defects, Congenital