Article

Zebrafish arterial valve development occurs through direct differentiation of second heart field progenitors

2024-04-20

Abstract excerpt

<h4>Aims</h4> Bicuspid Aortic Valve (BAV) is the most common congenital heart defect, affecting at least 2% of the population. The embryonic origins of BAV remain poorly understood, limiting the identification of assays for validating patient variants and ultimately causative genes for BAV. In both human and mouse, the left and right leaflets of the arterial valves arise from the outflow tract cushions, with inte...

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Literature Corpus work: c0cd2cbf-4e98-5ca7-87de-7c89da11c31d
DOI: 10.1101/2024.04.17.589935

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