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Article

Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.

Human genetics - 1 Jun 2013

Tin Adrienne, Astor Brad C, Boerwinkle Eric, Hoogeveen Ron C, Coresh Josef, Kao Wen Hong Linda

Abstract excerpt

Beta-2 microglobulin (B2M) is a component of the major histocompatibility complex (MHC) class I molecule and has been studied as a biomarker of kidney function, cardiovascular diseases and mortality. Little is known about the genes influencing its levels directly or through glomerular filtration rate (GFR). We conducted a genome-wide association study of plasma B2M levels in 6738 European Americans from the...

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Identifiers

PMID: 23417110
DOI: 10.1007/s00439-013-1274-7
PMCID: PMC3656139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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