Article
Associations between human leukocyte antigens and renal function.
Scientific reports - 4 Feb 2021
Lowe Marcus, Payton Antony, Verma Arpana, Worthington Judith, Gemmell Isla, Hamilton Patrick, Ollier William, Augustine Titus, Poulton Kay
Abstract excerpt
Human leukocyte antigens (HLA) have been associated with renal function, but previous studies report contradictory findings with little consensus on the exact nature or impact of this observation. This study included 401,307 white British subjects aged 39-73 when they were recruited by UK Biobank. Subjects' HLA types were imputed using HLA*IMP:02 software. Regression analysis was used to compare 362 imputed HLA...
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