Article
Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jun 2013
Tin Adrienne, Astor Brad C, Boerwinkle Eric, Hoogeveen Ron C, Coresh Josef, Kao W H Linda
Abstract excerpt
BACKGROUND: Beta-trace protein (BTP), measured in serum or plasma, has potential as a novel biomarker for kidney function. Little is known about the genes influencing BTP levels. METHODS: We conducted a genome-wide association study of log-transformed plasma BTP levels in 6720 European Americans (EAs) and replicated the significant associations in 1734 African Americans (AAs) from the Atherosclerosis Risk in...
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