Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of gremlin 1 (GREM1) as a candidate susceptibility gene for albuminuria-related traits in Mexican Americans with type 2 diabetes mellitus.

Metabolism: clinical and experimental - 1 Oct 2009

Thameem Farook, Puppala Sobha, He Xin, Arar Nedal H, Stern Michael P, Blangero John, Duggirala Ravindranath, Abboud Hanna E

Abstract excerpt

Several novel genes that are up-regulated in the kidney in diabetes have been identified including GREM1, which encodes gremlin 1. GREM1 maps to human chromosome 15q12, a region previously found to be linked to albumin to creatinine ratio (ACR) in Mexican Americans. The objective of this study is to investigate whether genetic variants in GREM1, a positional candidate gene, contribute to variation in ACR. By...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albuminuria
Share to Chromosomes, Human, Pair 15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Creatinine

Share to Diabetes Mellitus, Type 2

Share to Hemodynamics

Share to Intercellular Signaling Peptides and Proteins

Share to Linkage Disequilibrium

Share to Mexican Americans

Source

Open in PubMed Open full text

Identifiers

PMID: 19577778
DOI: 10.1016/j.metabol.2009.04.039
PMCID: PMC2913546

Genes

ACR
GREM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of gremlin 1 (GREM1) as a candidate susceptibility gene for albuminuria-related traits in Mexican Americans with type 2 diabetes mellitus.PMID 19577778Read ↗

Genetic variants in transient receptor potential cation channel, subfamily M 1 (TRPM1) and their risk of albuminuria-related traits in Mexican Americans.Semantic proximity Read ↗

A GREM1 gene variant associates with diabetic nephropathy.Semantic proximity Read ↗

Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994.Semantic proximity Read ↗

Genetic Factors in Diabetic NephropathySemantic proximity Read ↗

Evaluation of tight junction protein 1 encoding zona occludens 1 as a candidate gene for albuminuria in a Mexican American population.Semantic proximity Read ↗

Genome-wide association studies of albuminuria: towards genetic stratification in diabetes?Semantic proximity Read ↗

Investigation of known estimated glomerular filtration rate loci in patients with type 2 diabetes.Semantic proximity Read ↗

A genome-wide linkage scan for genes controlling variation in urinary albumin excretion in type II diabetesSemantic proximity Read ↗

ELMO1 variants and susceptibility to diabetic nephropathy in American Indians.Semantic proximity Read ↗

Development and validation of a multivariable genotype-informed gestational diabetes prediction algorithm for clinical use in the Mexican population: insights into susceptibility mechanisms.Semantic proximity Read ↗

Albuminuric and non-albuminuric reduced eGFR phenotypes in youth with type 1 diabetes: Factors associated with cardiometabolic risk.Semantic proximity Read ↗

Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.