Article
Isothermal amplification system based on template-dependent extension.
Chemical communications (Cambridge, England) - 25 Mar 2013
Zhou Hui, Xie Su-Jin, Zhang Song-Bai, Shen Guo-Li, Yu Ru-Qin, Wu Zai-Sheng
Abstract excerpt
A novel template-dependent extension based isothermal amplification (TEIA) system with high single-base discrimination capability is developed, where the interference caused by non-specific reaction in isothermal strand displacement amplification (SDA) technique is substantially avoided via using a functionalized template probe, showing potential value in the development and application of SDA based detection...
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