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Article

Hybridization-triggered isothermal signal amplification coupled with MutS for label-free and sensitive fluorescent assay of SNPs.

Chemical communications (Cambridge, England) - 7 Jun 2012

Jiao Anli, Zheng Jing, Hu Yaping, Zhu Guizhi, Li Jishan, Li Huimin, Yang Ronghua, Tan Weihong

Abstract excerpt

Combining the specific recognization of MutS protein for mismatched DNA sequences with the target-driven molecular switch that acts as both the template and primer of the polymerization reaction, a new label-free and sensitive fluorescent assay strategy for specific single-stranded DNA sequences or SNPs is proposed.

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Identifiers

PMID: 22549134
DOI: 10.1039/c2cc30882g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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