Article
Associations between polymorphisms in the antiviral TRIM genes and measles vaccine immunity.
Human immunology - 1 Jun 2013
Ovsyannikova Inna G, Haralambieva Iana H, Vierkant Robert A, O'Byrne Megan M, Poland Gregory A
Abstract excerpt
The role of polymorphisms within the antiviral tripartite motif (TRIM) genes in measles vaccine adaptive immune responses was examined. A limited association was found between TRIM5 (rs7122620) and TRIM25 (rs205499) gene polymorphisms and measles-specific antibody levels. However, many associations were found between TRIM gene SNPs and variations in cellular responses (IFN-γ Elispot and secreted cytokines IL-2,...
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