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Article

The role of polymorphisms in Toll-like receptors and their associated intracellular signaling genes in measles vaccine immunity.

Human genetics - 1 Oct 2011

Ovsyannikova Inna G, Haralambieva Iana H, Vierkant Robert A, Pankratz V Shane, Jacobson Robert M, Poland Gregory A

Abstract excerpt

Toll-like receptors (TLRs) and their intracellular signaling molecules play an important role in innate immunity. In this study, we examined associations between polymorphisms in TLR family genes and measles vaccine-specific immune responses. We genotyped 764 subjects (11-22 years old) after two doses of measles vaccine for TLR signaling SNP markers (n = 454). The major alleles of coding SNPs in the TLR2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Intracellular Signaling Peptides and Proteins

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Source

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Identifiers

PMID: 21424379
DOI: 10.1007/s00439-011-0977-x
PMCID: PMC3924423

Genes

TLR2
IKBKE
IRAK2
NFKBIA
TICAM1
TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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