Article
Multigenic control of measles vaccine immunity mediated by polymorphisms in measles receptor, innate pathway, and cytokine genes.
Vaccine - 9 Mar 2012
Kennedy Richard B, Ovsyannikova Inna G, Haralambieva Iana H, O'Byrne Megan M, Jacobson Robert M, Pankratz V Shane, Poland Gregory A
Abstract excerpt
Measles infection and vaccine response are complex biological processes that involve both viral and host genetic factors. We have previously investigated the influence of genetic polymorphisms on vaccine immune response, including measles vaccines, and have shown that polymorphisms in HLA, cytokine, cytokine receptor, and innate immune response genes are associated with variation in vaccine response but do not...
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