Article
A miR-151 binding site polymorphism in the 3'-untranslated region of the cyclin E1 gene associated with nasopharyngeal carcinoma.
Biochemical and biophysical research communications - 22 Mar 2013
Liu Ying, Cai Hongbing, Liu Jie, Fan Haoning, Wang Zhiyuan, Wang Qirui, Shao Meng, Sun Xuegang, Diao Jianxin, Liu Yuanliang, Shi Yusheng, Fan Qin
Abstract excerpt
Genetic alterations in nasopharyngeal carcinoma (NPC) have been reported in previous works. However, it remains unclear whether polymorphisms within the miRNA-target binding sites are associated with individual NPC risk. In this study, new experimental and computational approaches were developed to assess the polymorphism frequency distribution within the miRNA sites in NPC patients, and to explore its...
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