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Article

Single cell transcriptomic analysis of prostate cancer cells

16 Feb 2013

Abstract excerpt

BACKGROUND: The ability to interrogate circulating tumor cells (CTC) and disseminated tumor cells (DTC) is restricted by the small number detected and isolated (typically <10). To determine if a commercially available technology could provide a transcriptomic profile of a single prostate cancer (PCa) cell, we clonally selected and cultured a single passage of cell cycle synchronized C4-2B PCa cells. Ten sets of...

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PMID: 23414343
DOI: 10.1186/1471-2199-14-6

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