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Article

Glucocerebrosidase mutations influence the natural history of Parkinson's disease in a community-based incident cohort.

Brain : a journal of neurology - 1 Feb 2013

Winder-Rhodes Sophie E, Evans Jonathan R, Ban Maria, Mason Sarah L, Williams-Gray Caroline H, Foltynie Tom, Duran Raquel, Mencacci Niccolo E, Sawcer Stephen J, Barker Roger A

Abstract excerpt

Carriers of mutations in the glucocerebrosidase gene (GBA) are at increased risk of developing Parkinson's disease. The frequency of GBA mutations in unselected Parkinson's disease populations has not been established. Furthermore, no previous studies have investigated the influence of GBA mutations on the natural history of Parkinson's disease using prospective follow-up. We studied DNA from 262 cases who had...

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PMID: 23413260
DOI: 10.1093/brain/aws318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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