Article
Detection of soluble BAG3 and anti-BAG3 antibodies in patients with chronic heart failure
14 Feb 2013
Abstract excerpt
Bcl-2-associated athanogene 3 (BAG3) protein belongs to the family of co-chaperones that interact with the ATPase domain of the heat shock protein HSP70 through the BAG domain (amino acids 110–124). BAG3 contains also a WW domain, a proline-rich repeat (PXXP) and two conserved Ile-Pro-Val motifs that mediate binding to other proteins. 1 bag3 gene is constitutively expressed in a few normal cell types, including...
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