Article
Advances in the role and mechanism of BAG3 in dilated cardiomyopathy.
Heart failure reviews - 1 Jan 2021
Liu Leiling, Sun Kaijun, Zhang Xiaojun, Tang Ying, Xu Danyan
Abstract excerpt
The B cell lymphoma 2-associated anthanogene (BAG3) is an anti-apoptotic co-chaperone protein. Previous reports suggest that mutations in BAG3 are associated with dilated cardiomyopathy. This review aims to summarize the current understanding of the relationship between BAG3 mutations and dilated cardiomyopathy, primarily focusing on the role and protective mechanism of BAG3 in cardiomyocytes from individuals...
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