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Article

BAG3: a new player in the heart failure paradigm.

Heart failure reviews - 1 Jul 2015

Knezevic Tijana, Myers Valerie D, Gordon Jennifer, Tilley Douglas G, Sharp Thomas E, Wang JuFang, Khalili Kamel, Cheung Joseph Y, Feldman Arthur M

Abstract excerpt

BAG3 is a cellular protein that is expressed predominantly in skeletal and cardiac muscle but can also be found in the brain and in the peripheral nervous system. BAG3 functions in the cell include: serving as a co-chaperone with members of the heat-shock protein family of proteins to facilitate the removal of misfolded and degraded proteins, inhibiting apoptosis by interacting with Bcl2 and maintaining the...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25925243
DOI: 10.1007/s10741-015-9487-6
PMCID: PMC4463985

Genes

BAG3

Provenance

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Related research

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