Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis.

The Journal of allergy and clinical immunology - 1 Nov 2009

Philip George, van Adelsberg Janet, Loeys Thomas, Liu Nancy, Wong Peggy, Lai Eseng, Dass S Balachandra, Reiss Theodore F

Abstract excerpt

BACKGROUND: Prostaglandin D(2) is a proinflammatory mediator believed to be important in asthma and allergic rhinitis (AR). Allelic variants in the prostaglandin D(2) receptor type 1 (DP1) gene (PTGDR) have been suggested to be associated with asthma susceptibility. OBJECTIVES: We sought to investigate the efficacy of the DP1 antagonist laropiprant (alone or with montelukast) in asthma and seasonal AR and explore...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetates
Share to Anti-Asthmatic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cross-Over Studies

Share to Cyclopropanes

Share to Quinolines

Share to Receptors, Prostaglandin

Share to Rhinitis, Allergic, Seasonal

Share to Sulfides

Source

Identifiers

PMID: 19748656
DOI: 10.1016/j.jaci.2009.07.006

Genes

PTGDR
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis.PMID 19748656Read ↗

PTGDR gene in asthma: a functional, genetic, and epigenetic study.Semantic proximity Read ↗

The PTGDR gene is not associated with asthma in 3 ethnically diverse populations.Semantic proximity Read ↗

Role of prostaglandin D(2) and its receptors in the pathophysiology of asthma.Semantic proximity Read ↗

The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases.Semantic proximity Read ↗

Promoter genetic variants of prostanoid DP receptor (PTGDR) gene in patients with asthma.Semantic proximity Read ↗

PTGDR polymorphisms and susceptibility to asthma: a meta-analysis.Semantic proximity Read ↗

Efficacy and safety of desloratadine and phenylephrine for the control of symptoms associated with allergic rhinitis: A systematic review with meta-analysisSemantic proximity Read ↗

Rhinitis 2020: A practice parameter update.Semantic proximity Read ↗

Null association between serum 25-hydroxyvitamin D levels with allergic rhinitis, allergic sensitization and non-allergic rhinitis: A Mendelian randomization study.Semantic proximity Read ↗

Role of prostanoid DP receptor variants in susceptibility to asthma.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in the F2RL1 gene with clinical and inflammatory characteristics of patients with asthmaSemantic proximity Read ↗

Association of VDR and CYP2R1 Polymorphisms with Mite-Sensitized Persistent Allergic Rhinitis in a Chinese Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.