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Article

CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness.

Nucleic acids research - 1 Apr 2013

Pereira Bruno, Sousa Sofia, Barros Rita, Carreto Laura, Oliveira Patrícia, Oliveira Carla, Chartier Nicolas T, Plateroti Michelina, Rouault Jean-Pierre, Freund Jean-Noël, Billaud Marc, Almeida Raquel

Abstract excerpt

The homeobox transcription factor CDX2 plays a crucial role in intestinal cell fate specification, both during normal development and in tumorigenic processes involving intestinal reprogramming. The CDX2 regulatory network is intricate, but it has not yet been fully uncovered. Through genome-wide screening of a 3D culture system, the RNA-binding protein MEX3A was identified as putatively involved in CDX2...

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Source

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Identifiers

PMID: 23408853
DOI: 10.1093/nar/gkt087
PMCID: PMC3627580

Genes

CDX2
BMI1
MSI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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