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Article

Cell type-specific autoregulation of the Caudal-related homeobox gene Cdx-2/3.

The Journal of biological chemistry - 26 Nov 1999

Xu F, Li H, Jin T

Abstract excerpt

The caudal-related homeobox gene Cdx-2/3 is a critical "master" control gene in embryogenesis. Mice heterozygous for a null mutation in Cdx-2/3 exhibit multiple malfunctions including tail abnormalities, stunted growth, a homeotic shift in vertebrae, and the development of multiple intestinal adenomatous polyps, indicating that Cdx-2/3 is haplo-insufficient. In vitro studies have identified more than a half-dozen...

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Source

Identifiers

PMID: 10567407
DOI: 10.1074/jbc.274.48.34310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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