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Article

Different effects of the Cdx1 and Cdx2 homeobox genes in a murine model of intestinal inflammation.

Gut - 1 Dec 2007

Calon A, Gross I, Lhermitte B, Martin E, Beck F, Duclos B, Kedinger M, Duluc I, Domon-Dell C, Freund J-N

Abstract excerpt

AIMS: The CDX1 and CDX2 homeoproteins are intestine-specific transcription factors regulating homeostasis. We investigated their relevance in experimentally-induced intestinal inflammation. METHODS: The response to intestinal inflammation induced by dextran sodium sulfate (DSS) was compared in wild type, Cdx1(-/-) and Cdx2(+/-) mice. Intestinal permeability was determined in wild type and Cdx2(+/-) mice....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 17595234
DOI: 10.1136/gut.2007.125542
PMCID: PMC2095714

Genes

SMAD3
CDX1
CDX2
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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