Article
A mutation in the start codon of γ-crystallin D leads to nuclear cataracts in the Dahl SS/Jr-Ctr strain.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2013
Johnson Ashley C, Lee Jonathan W, Harmon Ashlyn C, Morris Zaliya, Wang Xuexiang, Fratkin Jonathan, Rapp John P, Gomez-Sanchez Elise, Garrett Michael R
Abstract excerpt
Cataracts are a major cause of blindness. The most common forms of cataracts are age- and UV-related and develop mostly in the elderly, while congenital cataracts appear at birth or in early childhood. The Dahl salt-sensitive (SS/Jr) rat is an extensively used model of salt-sensitive hypertension...
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