Article
The new mutation L321F in Candida albicans ERG11 gene may be associated with fluconazole resistance.
Revista iberoamericana de micologia - 1 Jan 2000
Oliveira Carvalho Vagner, Okay Thelma S, Melhem Márcia S C, Walderez Szeszs Maria, del Negro Gilda M B
Abstract excerpt
BACKGROUND: For many years fluconazole has been commonly used to treat Candida infections. However, the indiscriminate use of this antimycotic therapy has favored the emergence of resistant isolates. Mutations in the ERG11 gene have been described as one of the primary mechanisms of resistance in...
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