Article
Association of T916C (Y257H) mutation in Candida albicans ERG11 with fluconazole resistance.
Mycoses - 1 May 2013
Zhao Jie, Xu Yonghao, Li Chunyang
Abstract excerpt
Repeated and prolonged use of fluconazole in treating candidosis leads to drug resistance. The aim of this study was to confirm the relationship between T916C (Y257H) mutation in Candida albicans ERG11 and fluconazole resistance. We replaced one copy of ERG11 with ERG11 containing the T916C mutat...
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