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Investigation of mutations in Erg11 gene of fluconazole resistant Candida albicans isolates from Turkish hospitals.

Mycoses - 1 Mar 2011

Manastır Lerzan, Ergon M Cem, Yücesoy Mine

Abstract excerpt

Widespread use of fluconazole has resulted in resistance in strains of Candida. The aim of our study was to investigate Y132H and other mutations in the ERG11 gene in conferring fluconazole resistance to C. albicans isolates. Seven fluconazole-resistant (R)/susceptible dose-dependent (SDD)/trailing and 10 fluconazole-susceptible (S) isolates were included. Restriction enzyme analysis was performed on all isolates...

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Identifiers

PMID: 19732347
DOI: 10.1111/j.1439-0507.2009.01766.x

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