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Susceptibility of clinical isolates of Candida species to fluconazole and detection of Candida albicans ERG11 mutations

24 Jan 2008

Abstract excerpt

OBJECTIVES: To investigate fluconazole susceptibility of Candida albicans from non-AIDS patients and to analyse the relationship between mutations in the ERG11 gene of these isolates and fluconazole resistance. METHODS: Four hundred and twenty-six clinical isolates of Candida species were collected. Fluconazole susceptibility was tested in vitro using microdilution and disc diffusion assays. The ERG11 genes of 23...

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PMID: 18218640
DOI: 10.1093/jac/dkn015

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