Article

ERG11 mutations are associated with high-level azole resistance in clinical Candida tropicalis isolates, a Singapore study

2017-03-01

Abstract excerpt

Candida tropicalis is a commonly isolated non-albicans Candida in Asia. In this clinical microbiology laboratory study, a total of 1579 C. tropicalis were isolated during 2009–2014 and of these 348 isolates were tested for azole susceptibility. We show that the current rates of fluconazole resistance in C. tropicalis increased from 2.9% in 2009–2011 to 9% in 2012–2014 (P = 0.03). High fluconazole minimum inhibitor...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4314aeb2-d254-5966-969f-87a7420e9ed9
DOI: 10.1016/j.myc.2016.11.001

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ERG11 mutations are associated with high-level azole resistance in clinical Candida tropicalis isolates, a Singapore studyDOI 10.1016/j.myc.2016.11.001Read

Azole Resistance and ERG11 Mutation in Clinical Isolates of Candida tropicalisSemantic proximity Read

Mechanisms of azole antifungal resistance in clinical isolates of Candida tropicalisSemantic proximity Read

MDR1 overexpression combined with ERG11 mutations induce high-level fluconazole resistance in Candida tropicalis clinical isolates.Semantic proximity Read

Recent Increase in the Prevalence of Fluconazole-Non-susceptible Candida tropicalis Blood Isolates in Turkey: Clinical Implication of Azole-Non-susceptible and Fluconazole Tolerant Phenotypes and GenotypingSemantic proximity Read

Antifungal susceptibility, genotyping, resistance mechanism, and clinical profile of Candida tropicalis blood isolates.Semantic proximity Read

Genotyping and susceptibility testing uncovers large azole-resistant Candida tropicalis clade in Alexandria, Egypt.Semantic proximity Read

Molecular analysis of ERG11 gene in azole resistant Candida Species among immunocompromised patientsSemantic proximity Read

A predominant genotype of azole-resistant Candida tropicalis clinical strainsSemantic proximity Read

Hotspot mutations and genomic expansion of ERG11 are major mechanisms of azole resistance in environmental and human commensal isolates of Candida tropicalis.Semantic proximity Read

General hospital outbreak of invasive candidiasis due to azole-resistant Candida parapsilosis associated with an Erg11 Y132F mutation.Semantic proximity Read

Overexpression of efflux pump transporter genes and mutations in ERG11 pave the way to fluconazole resistance in Candida tropicalis: A study from a North India region.Semantic proximity Read

Azole Resistance in Candida albicans Isolates from Oropharyngeal Candidiasis is Associated with ERG11 Mutation and Efflux OverexpressionSemantic proximity Read