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Article

Engineering new protein-protein interactions on the β-propeller fold by yeast cell surface display.

Chembiochem : a European journal of chemical biology - 4 Mar 2013

Zhang Keya, Li Heng, Bhuripanyo Karan, Zhao Bo, Chen Tiffany F, Zheng Ning, Yin Jun

Abstract excerpt

REINVENTING THE WHEEL: The β-propeller domain folds like a wheel to provide key protein-protein interactions in the cell. Here we used high-throughput yeast sorting to "invent" β-propellers of new binding specificities with cellular targets.

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23401304
DOI: 10.1002/cbic.201200718
PMCID: PMC3822001

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