Long term effect on lung function of alpha 1-protease inhibitor substitution therapy in COPD patients with Pi ZZ phenotype.

Article

Long term effect on lung function of alpha 1-protease inhibitor substitution therapy in COPD patients with Pi ZZ phenotype.

The European respiratory journal. Supplement - 1 Mar 1990

Ulmer W T, Schmidt E W, Rasche B

Abstract excerpt

Eight patients suffering from alpha 1-protease inhibitor (alpha 1-PI) deficiency (Pi ZZ phenotype) and chronic obstructive lung disease received substitution therapy (60 mg.kg-1 weekly) for a period of up to 30 months. Intrathoracic gas volume, airway resistance and arterial oxygen tension were f...

Topics

Airway Resistance
Humans
Lung Diseases, Obstructive
Oxygen
Phenotype
Pulmonary Gas Exchange
alpha 1-Antitrypsin
alpha 1-Antitrypsin Deficiency

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