[Evaluation after 2 years of substitutive treatment of PiZZ emphysema with alpha-1 antitrypsin. 9 cases].

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Article

[Evaluation after 2 years of substitutive treatment of PiZZ emphysema with alpha-1 antitrypsin. 9 cases].

Presse medicale (Paris, France : 1983) - 24 Mar 1990

Carles P, Constans J, Pujazon M C, Arnaud J, Lauque D, Goudemand M

Abstract excerpt

Homozygous PiZZ individuals with a serum deficiency due to a defect in the secretion of the alpha 1-antitrypsin protein are at risk of developing severe panlobular emphysema. Tobacco smokers are particularly exposed to the disease which begins at an earlier age. Treatment by substitutive therapy...

Topics

Adult
Clinical Protocols
Follow-Up Studies
Humans
Infusions, Intravenous
Male
Middle Aged
Phenotype
Pulmonary Emphysema
Pulmonary Wedge Pressure
Respiratory Function Tests
alpha 1-Antitrypsin
alpha 1-Antitrypsin Deficiency

Source

Open in PubMed

Identifiers

PMID: 2138750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2138750-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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