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[Clinical aspects, results of diagnostic pulmonary function tests and biochemical parameters in children with homozygote alpha-1-antitrypsin deficiency].

Pneumologie (Stuttgart, Germany) - 1 Oct 1990

Paul K, Heck B, Schulz V, Ebert W, Trefz G, Feist D

Abstract excerpt

The clinical course and pulmonary function tests of individuals with severe Alpha-1-Antitrypsin (Alpha-1-AT) deficiency reveal a marked interindividual variability. 4 patients with PI type ZZ and 2 patients with PI type SZ had been identified by neonatal cholestasis. None had pulmonary symptoms a...

Topics

Adolescent
Child
Female
Humans
Lung
Male
Metabolism, Inborn Errors
Phenotype
Protease Inhibitors
Respiratory Function Tests
alpha 1-Antitrypsin
alpha 1-Antitrypsin Deficiency

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PMID: 2281074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2281074-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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