Article
Longitudinal follow-up of patients with alpha(1)-protease inhibitor deficiency before and during therapy with IV alpha(1)-protease inhibitor.
Chest - 1 Mar 2001
Wencker M, Fuhrmann B, Banik N, Konietzko N
Abstract excerpt
BACKGROUND: The efficacy of IV augmentation therapy with human alpha(1)-protease inhibitor (alpha(1)-Pi) in patients with severe alpha(1)-Pi deficiency is still under debate. STUDY OBJECTIVES: To evaluate the progression of emphysema in patients with alpha(1)-Pi deficiency before and during a period in which they received treatment with alpha(1)-Pi. DESIGN: Multicenter, retrospective cohort study. SETTING:...
Topics
- Cohort Studies
- Disease Progression
- Follow-Up Studies
- Forced Expiratory Volume
- Humans
- Infusions, Intravenous
- Phenotype
- Pulmonary Emphysema
- Retrospective Studies
- Smoking
- Time Factors
- alpha 1-Antitrypsin
- alpha 1-Antitrypsin Deficiency