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Article

Decline in pulmonary function in patients with alpha 1-antitrypsin deficiency.

Lung - 1 Jan 1990

Evald T, Dirksen A, Keittelmann S, Viskum K, Kok-Jensen A

Abstract excerpt

Sixty-five patients with severe alpha 1-antitrypsin (AAT) deficiency (phenotype PiZ) were followed with spirometry at regular intervals of one year and a median observation period of four years. The annual decline in pulmonary function was adjusted for sex, age and height by division with the predicted normal pulmonary function. The median decline in FEV1 was 1.9% predicted/year. The rate of decline was...

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Source

Identifiers

PMID: 2117166
DOI: 10.1007/BF02718180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Decline in pulmonary function in patients with alpha 1-antitrypsin deficiency.PMID 2117166Read ↗

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