Article
Risk factors for reduced pulmonary function in women. A possible relationship between Pi phenotype, number of children, and pulmonary function.
Chest - 1 Jul 1992
Horne S L, Chen Y, Cockcroft D W, Dosman J A
Abstract excerpt
Smoking and severe deficiency of protease inhibitor (Pi Z phenotype) both contribute significantly to the development of chronic obstructive pulmonary disease (COPD). The role of moderate Pi deficiency (Pi MZ phenotype) remains controversial. During a community-wide study of respiratory health which included 1,633 individuals, of whom 897 were women, we measured forced vital capacity (FVC), forced expired flow in...
Topics
- Adult
- Female
- Humans
- Linear Models
- Middle Aged
- Parity
- Phenotype
- Pulmonary Ventilation
- Risk Factors
- Smoking
- Vital Capacity
- alpha 1-Antitrypsin Deficiency