Article
Thiopurine S-methytransferase gene polymorphism in rheumatoid arthritis.
Archives of medical research - 1 Feb 2013
Elawi Asma M, Irshaid Yacoub M, Ismail Said I, Mustafa Khader N
Abstract excerpt
BACKGROUND AND AIMS: Thiopurine S-methyltransferase (TPMT) is responsible for inactivation of thiopurine drugs which are commonly used in leukemia, organ transplantation and autoimmune diseases. The gene encoding TPMT is polymorphic, and both phenotyping and genotyping studies have shown ethnic v...
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