Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic analysis of thiopurine methyltransferase polymorphism in the Jordanian population.

European journal of clinical pharmacology - 1 Oct 2010

Hakooz Nancy, Arafat Tawfiq, Payne Debbie, Ollier William, Pushpakom Sudeep, Andrews Julie, Newman William

Abstract excerpt

UNLABELLED: This study provides the first analysis of the TPMT mutant allele frequency in a sample of the Jordanian population and indicates that TPMT*3A is the most common allele in Jordanian subjects. PURPOSE: thiopurine methyltransferase TPMT catalyses the S-methylation of thiopurine drugs such as 6-mercaptopurine, 6-thioguanine, and azathiopurine. Thiopurine methyltransferase (TPMT) polymorphisms are the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arabs
Share to Europe
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Jordan

Share to Methyltransferases

Share to Polymorphism, Single Nucleotide

Share to Reference Values

Share to White People

Source

Identifiers

PMID: 20521035
DOI: 10.1007/s00228-010-0826-1

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic analysis of thiopurine methyltransferase polymorphism in the Jordanian population.PMID 20521035Read ↗

The frequency and distribution of thiopurine S-methyltransferase alleles in south Iranian population.Semantic proximity Read ↗

Thiopurine S-methytransferase gene polymorphism in rheumatoid arthritis.Semantic proximity Read ↗

The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations.Semantic proximity Read ↗

Genetic polymorphism of thiopurine S-methyltransferase: clinical importance and molecular mechanisms.Semantic proximity Read ↗

Frequency of thiopurine S-methyltransferase (TPMT) alleles in southeast Iranian population.Semantic proximity Read ↗

Genetic analysis of thiopurine methyltransferase polymorphism in a Japanese population.Semantic proximity Read ↗

Polymorphisms of the thiopurine S-methyltransferase gene among the Libyan population.Semantic proximity Read ↗

Genetic Polymorphism of Thiopurine S-Methyltransferase: Molecular Mechanisms and Clinical ImportanceSemantic proximity Read ↗

Clinical pharmacogenomics of thiopurine S-methyltransferase.Semantic proximity Read ↗

Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms.Semantic proximity Read ↗

Assessment of thiopurine S-methyltransferase allele frequencies and phenotype-genotype concordance in a Tunisian population.Semantic proximity Read ↗

Thiopurine S-methyltransferase (TPMT) activity is better determined by biochemical assay versus genotyping in the Jewish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.