Article
Genetic risk factors for type 1 diabetes.
Lancet (London, England) - 4 Jun 2016
Pociot Flemming, Lernmark Åke
Abstract excerpt
Type 1 diabetes is diagnosed at the end of a prodrome of β-cell autoimmunity. The disease is most likely triggered at an early age by autoantibodies primarily directed against insulin or glutamic acid decarboxylase, or both, but rarely against islet antigen-2. After the initial appearance of one of these autoantibody biomarkers, a second, third, or fourth autoantibody against either islet antigen-2 or the ZnT8...
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