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Article

Genetic landscape of recurrent ASXL1, U2AF1, SF3B1, SRSF2, and EZH2 mutations in 304 Chinese patients with myelodysplastic syndromes.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2016

Wu Lingyun, Song Luxi, Xu Lan, Chang Chunkang, Xu Feng, Wu Dong, He Qi, Su Jiying, Zhou Liyu, Xiao Chao, Zhang Zheng, Zhao Youshan, Chen Saijuan, Li Xiao

Abstract excerpt

We determined the biological and prognostic significance of five recurrent genetic aberrations in Chinese patients with myelodysplastic syndromes (MDS). A total of 304 Chinese MDS patients were screened for known mutations in five genes (ASXL1, U2AF1, SF3B1, SRSF2, and EZH2) using next-generation sequencing. Of these, 97 patients (31.9 %) harbored at least one mutation in the five genes, and patients harboring...

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Source

Identifiers

PMID: 26508027
DOI: 10.1007/s13277-015-4305-2

Genes

SRSF2
ASXL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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