Article
Copy number variations in IL22 gene are associated with Psoriasis vulgaris.
Human immunology - 1 Jun 2013
Prans Ele, Kingo Külli, Traks Tanel, Silm Helgi, Vasar Eero, Kõks Sulev
Abstract excerpt
Psoriasis vulgaris (PsV) is a frequent, chronically relapsing, immune-mediated systemic disease with characteristic skin changes. IL22 is a cytokine of IL10 family, with significant proliferative effect on different cell lines. Copy number variations (CNV) have been discovered to have phenotypic consequences and are associated with various types of diseases. In the work presented here we analyzed the copy number...
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