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Article

Copy number variation of beta-defensins and relevance to disease.

Cytogenetic and genome research - 1 Jan 2008

Hollox E J

Abstract excerpt

Beta-defensins are multifunctional proteins that have an important role in the innate immune system. A cluster of beta-defensin genes shows common and extensive variation in copy number in humans. This copy number has been associated with differing susceptibility to Crohn's disease and psoriasis. In this review, I summarise what is currently known about copy number variation (CNV) of beta-defensins, and discuss...

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Source

Identifiers

PMID: 19287149
DOI: 10.1159/000184702

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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